This capability helps in designing a complex system of an intelligent and strong. This book includes a sample of the research on innovative application of advanced computational intelligence paradigms. Characteristics of computational intelligence paradigms such as learning, generalization based on the knowledge learned, extracting knowledge from data are inaccurate and incomplete is very important for the implementation of intelligent machines. The chapters include computational intelligence paradigm architecture, knowledge discovery, pattern classification, cluster, support vector machines and gene linkage analysis.