Genetic Programming Theory and Practice V was developed from the fifth workshop at the University of Michigan's Center? For the Study of Complex Systems to facilitate the exchange of ideas and information related to the thriving field of Genetic Programming (GP). The text explores the synergy between theory and practice, producing a comprehensive view of the state of the art in GP applications. Work involves the application of GP for a variety of domains, including bioinformatics, symbolic regression for system modeling, financial modeling, circuit design and robot controllers.